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Systane COMPLETE PF Multi-Dose Dry Eye Drops

Curated from 95 real Reddit conversations

Refreshed on: April 11, 2025

Systane COMPLETE PF Multi-Dose Dry Eye Drops

Brand: Systane
Price: $21
Snoop Score:
8.5
Sentiment
8.2
Popularity
9.4
Technical
7.9

Snoop's Take

Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops are specially formulated to provide fast-acting hydration for sensitive eyes, making them an ideal solution for individuals suffering from dry eye symptoms. These drops utilize nano droplets for enhanced coverage and tear evaporation protection, ensuring long-lasting relief and comfort for users. Consumer sentiment surrounding Systane COMPLETE PF is largely positive, with many users praising its effectiveness for treating dry eye issues, both in themselves and their pets. One user noted, "They’ve cleared up my piggies eye issues many times, literally saved me hundreds in vet visits." Additionally, the preservative-free formula has gained favor among those with sensitive eyes, as it provides relief without the risk of irritation, with comments like, "It is preservative free, but it's in a bottle not in single uses." Overall, Systane COMPLETE PF is highly recommended within its category for those seeking effective relief from dry eye symptoms. The combination of positive feedback regarding its soothing properties and effectiveness suggests that it is a reliable choice for users looking for a quality dry eye treatment.

Not for you? Check out our other rated Eye Care

He now uses Systane a few times a day, as directed by the vet.

Positive Feedback

The lasik took slight dry eyes to bad.

Negative Feedback
Product
8.5
Systane COMPLETE PF Multi-Dose Dry Eye Drops
Redness Relief
6 / 10
Dry Eye Moisturization
10 / 10
Post-Surgery Care
10 / 10
Daily Comfort Maintenance
10 / 10
See how this compares to all Eye Care

What it does well!

Key strengths users can’t stop talking about.
Effective for dry eye treatment
He now uses Systane a few times a day, as directed by the vet.
Any time his eye waters then dries...I don't feel like the washcloth does anything.
It may not be a bad idea to take them to the vet for a lacrimal flush.
Effective for eye issues in pets
They’ve cleared up my piggies eye issues many times, literally saved me hundreds in vet visits.
I don’t think it’s something you’d want to use on the regular if there are no symptoms or issues though.
It helps get the goopies out of her eye and really makes a difference with her dry eyes.
Recommended by doctors for effective relief
I guess my question is, 1. how dumb am I and 2. did I just potentially just put bacteria in my eye.
No negative effects reported by long-term users
I've been using them daily for a year with no negative effects.
Good lubrication and long-lasting effect
good lubrication, lasts pretty long and does not get all sticky when it dries.
Provides more relief compared to other variants
I find more relief! Keep them refrigerated for even more relief.
Preservative-free for sensitive eyes
It is preservative free, but it's in a bottle not in single uses.
Yes it’s safe - much easier to use than the refresh PF bottle too.
Effective for dry eye relief post-LASIK
The sales pitch that you save money on no more glasses or contacts is BS.
The journey was not fun but it is what it is.
Preferred over other brands for ease of use
I prefer their Hydration PF over the Complete PF.
Nano lipid lubricant effective for evaporative dry eye
Complete is a nano lipid lubricant; it’s designed for evaporative (lipid) deficiency (MGD). Preservative free is gentler on the eye surface than preserved.
Preservative-free version is preferred
it is better than ultra.
Soothing effect reported
Its soothing but the relief didn't last very long.
Recommended by veterinarians for pets
the brand we recommend at my work is “systane”
From now on I will take eye injuries very seriously and not try to self treat.

Where it needs some work!

Areas to watch—feedback on possible improvements.
Ongoing dry eye issues after LASIK
The lasik took slight dry eyes to bad.
Stings upon application
They sting like the devil when I first put them in.
My eyes felt like they were on fire 🔥 with the Complete PF.

Compare On All Talked About Dimensions

Product NameImagePriceScoreCompareSee DetailsBuy Now
Systane COMPLETE PF Multi-Dose Dry Eye DropsSystane COMPLETE PF Multi-Dose Dry Eye Drops$21
8.5
DetailsBuy
Systane Ultra Lubricant Eye DropsSystane Ultra Lubricant Eye Drops$15
8.1
DetailsBuy
LUMIFY Redness Reliever Eye DropsLUMIFY Redness Reliever Eye Drops$22
7.7
DetailsBuy
LUMIFY Redness Reliever Eye DropsLUMIFY Redness Reliever Eye Drops$11
7.7
DetailsBuy
Systane Ultra Lubricant Eye DropsSystane Ultra Lubricant Eye Drops$5
6.8
DetailsBuy
Refresh Tears Lubricant Eye Drops, 2 Bottles .5 fl ozRefresh Tears Lubricant Eye Drops, 2 Bottles .5 fl oz$14
6.1
DetailsBuy
Refresh Plus Lubricant Eye Drops - 30 CountRefresh Plus Lubricant Eye Drops - 30 Count$10
6.0
DetailsBuy
Toneur Dermafuse Patches for Eye BagsToneur Dermafuse Patches for Eye Bags$20
4.4
DetailsBuy
Esplendor Winner World Eye Drops – 15mlEsplendor Winner World Eye Drops – 15ml$51
4.1
DetailsBuy
Generic 2pcs Easy Peel-Off Eyebrow GelGeneric 2pcs Easy Peel-Off Eyebrow Gel$22
2.5
DetailsBuy
Generic 24K Gold Under Eye Patch with CollagenGeneric 24K Gold Under Eye Patch with Collagen$8
1.1
DetailsBuy

Core Power Plays

The specs and strengths that make it shine.
Discussion about eye conditions leading to use of eye drops
Anyone know what could be causing his eye to be like this?
Mine had conjunctivitis earlier this year and it was quite similar to this.
Same happened to mine and eye drops from vet cleared it up.
My vet said she wasn't eager to flush because he would need to be sedated.
Discussion about different Systane eye drop variants
Both "ultra" and "hydration" have worked for me (besides the annoyance of having to keep putting more drops in every hour or two) but it would be nice to know for sure.
Discussion about sustainable packaging for eye drops
Naturally, eye drops come in...a *lot* of plastic.
You shouldn’t give up the eye drops or feel like you should because of plastic packaging - having dry eyes is horrible.
I'm just using Hylo Comod for now, as they are the only ones I found that come in a bigger bottle, and don't go bad for a longer time.
if anyone is interested in more talk about veganism and zero waste, you should also check out /r/ZeroWasteVegans!
Fun fact about cat sleep habits
It may be a little creepy to you but it's a perfectly normal thing for your cat to do :)

Hidden Hero Hacks

Unexpected tricks and side‑door uses you’ll love.
Discussion about alternative treatments for eye issues
It is literally amazing. It's a little gel you put directly on their eyeball.
I think if you wanted to use anything to regularly flush out his eye, any 'liquid tears' should work.
My vet said is was safe to use for piggies.
Discussion about veterinary eye drop recommendations
Dog goggles are pretty great too.

Buyer’s Cheat Sheet

What to check before you click ‘Add to Cart.’
Difficulty in finding the product available
Soooo frustrating. Some of us can’t use ointments.
I’m so glad I found this. What I do find is outrageously over priced.
Confusion about product usage and directions
When you say shake, do you mean shake like you would to mix something?
Preservative-free used to be single-use vials like Refresh Plus, but to save the planet and keep costs down they are going to these bigger multi-use bottles.
ooh this is helpful! i should have come here first before using!
Discussion about cherry eye treatment for dogs
I come seeking advice regarding my three-month-old puppy, as I have recently noticed the presence of cherry eyes.
Yes, seek professional assistance & they will take care of it.
Avoid the putting your dog through that repetitive trauma.
Sound advice, forgot what the operation is, but it’s pretty cheap.
Discussion about alternative eye drops
I'm using the one with flaxseed oil and it feels ... amazing ....
Concerns about LASIK recovery and eye health
I am glad they work! I am just 1 week post-LASIK LASIK but I wonder if I will see any improvement.
Comparison between Systane Complete and other brands
What brand of eye drops should I use?
Overwhelming number of choices for artificial tears
In general I find artificial tears underwhelming but even though I only recently started the manuka forte it blows everything else out of the water.
Recommendations for alternative products
This one dry eye optometrist recommends Systane Hydration PF and Refresh Relieva, for aqueous deficiency.
Comparison of different Systane variants
Which one is better? Systane Hydration PF or Systane Complete Optional Dry Eye Relief?
how is the mega3 compared to the 2 systane ??
I think the holy grail of eye drops, if they ever create one, would be having 3 effective lubricating ingredients combined with the hydroboost technology of the Alcon Systane brand.

Cautionary Callouts

Know the pitfalls before they catch you off guard.
Discussion about eye drops for corrective surgery-related dry eyes
Would you happen to know which deficiency is caused by corrective eye surgery, and/or which eye drop is best for dry eyes caused by having said surgery?
Discussion about dog eye health issues
Happy thoughts for my baby please, she is having trouble keeping her right eye open and there is some kind of gunk coming out of it.
He's very delicate for a 100+ pound hippo.
Scared the crap out of me - turned out to basically be doggy pink eye.
Likely conjunctivitis - easily treatable!
Concerns about self-treatment for eye injuries
Hoping for the best!
Concerns about using human eye drops on dogs
I noticed after my dog came back inside this afternoon he hasn't been opening his eyelid.
I wouldn’t recommend using human eyedrops on your dog without understanding whats causing the issue.
Don’t use human eye drops.
**Don't.** My dog had some allergy issues and I checked with a vet about this - it's not safe for the dog.
Experience with a colleague's sleep apnea and open-eye sleeping
I didn't sleep at all for 3 days.

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