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Desitin Daily Defense Baby Diaper Rash Cream

Curated from 151 real Reddit conversations

Refreshed on: January 29, 2025

Desitin Daily Defense Baby Diaper Rash Cream

Brand: Desitin

Price: $4

Snoop Score:

7.1

Sentiment

7.7

Popularity

7.8

Technical

6.3

Buy on Amazon for $4 See All Diaper Creams Reviews

As an Amazon Associate, I earn from qualifying purchases.

Snoop's Take

Desitin Daily Defense Baby Diaper Rash Cream is designed to soothe, treat, and prevent diaper rash, making it an essential item for parents. This hypoallergenic cream features zinc oxide, which forms a protective barrier on your baby's skin, providing fast relief from the first signs of diaper rash. Consumer sentiment reflects a mix of experiences; while many users praise its effectiveness, stating, "This is the only thing we use that works!" others have reported issues for babies with sensitive skin, mentioning, "Desitin DOES NOT work for our LO who has sensitive skin." The cream is highly regarded for its soothing properties, with some parents noting it works quickly, stating, "It works so fast," while others prefer alternative products due to irritation concerns. Overall, Desitin Daily Defense is recommended for its effectiveness in treating and preventing diaper rash, particularly for those without sensitive skin, making it a staple in many households.

Not for you? Check out our other rated Diaper Creams

We use that and it treats diaper rash well.
Positive Feedback

Desitin DOES NOT work for our LO who has sensitive skin.
Negative Feedback

7.1

Desitin Daily Defense Baby Diaper Rash Cream

Buy on Amazon for $4

Treating Diaper Rash Discomfort

3 / 10

Preventing Rash with Barrier Protection

10 / 10

Daily Gentle Care for Sensitive Skin

3 / 10

Overnight Protection

9 / 10

See how this compares to all Diaper Creams

What it does well!

Key strengths users can’t stop talking about.

Effective at treating diaper rash for some users

“We use that and it treats diaper rash well.”➕

“Yup. This cream is awesome 👌”➕

“So far rashes have cleared in 1-2 applications.”➕

“Something in Desitin bothered my son's skin and I found Aquaphor to be better for him.”➕

Effective for treating diaper rash

“Your baby’s butt will be like a plastered wall at the end but the rash will go quick.”➕

“she said to use one that was white like Desitin because they work best and to start right away.”➕

“Never had any diaper rash issues.”➕

Soothing for skin irritations

“i trust my doctor and i know it’s for baby’s so it must be sensitive enough for adults.”➕

“The zinc oxide is an anti inflammatory and it’s just so soothing.”➕

“It's amazing.”➕

“we haven't had one in months.”➕

Effective for preventing diaper rash

“He’s barely had any rashes this way :)”➕

“if we don't slather down her butt before the overnight she wakes up with a rash.”➕

“haven’t had a diaper rash since she was 2 weeks old.”➕

Effective at treating diaper rash

“Diaper rash cream What is your preferred cream to *treat* diaper area rashes? My LO seems prone espe”➕

“Desitin works soooo good for us, both at treating and preventing.”➕

“This stuff is LEGIT.”➕

Works quickly for diaper rash relief

“It works so fast.”➕

“An overnight miracle.”➕

Recommended by pediatricians

“this was the only thing they would recommend.”➕

Users feel it's essential for diaper changes

“Can’t live without it!”➕

“There is nothing like it.”➕

Effective barrier for preventing diaper rash

“I found that I always applied ointment for every diaper change, and my son doesn’t ever get rashes anymore.”➕

“Desitin is just zinc and safe.”➕

Clinically recommended for frequent use

“I’ve definitely used diaper cream multiple times a day for a while after a bad diaper rash.”➕

Contains zinc oxide for skin integrity

“Zinc is anti-inflammatory and also essential in maintaining the integrity of cell walls.”➕

Effective for post-run treatment

“It doesn't burn like other brands on raw skin.”➕

Works great for multi-day adventures

“Seems to work great even for multi day adventures.”➕

Provides waterproofing effect

“It's quite sticky. Which is also its superpower.”➕

Highly effective for treating diaper rash

“This stuff is the only thing that saved our newborn’s sanity when they had a rash.”➕

“it’s the only diaper cream that works for my youngest kid.”➕

Effective for sensitive skin when mixed with other products

“What do you need and how do you keep their butts from getting red?”➕

“we slather it on like icing a cupcake.”➕

Where it needs some work!

Areas to watch—feedback on possible improvements.

Causes diaper rash for some babies with sensitive skin

“Desitin DOES NOT work for our LO who has sensitive skin.”➕

“Little diaper rash turned into a big issue after applying it.”➕

“I feel like it’s making it worse.”➕

“I really don’t like using destine.”➕

Fragrance may irritate sensitive skin

“Desitin Max Strength has fragrance, so maybe your baby is sensitive to that?”➕

May cause irritation for sensitive skin

“Things with zinc oxide IMO should only be used when your baby actually has a rash.”➕

“I know other babies who never used it and never had diaper rash.”➕

May dry out skin and cause peeling

“The desitin ended up drying her skin so bad she started to peel down there on top of her rash.”➕

Some users prefer alternative products for diaper rash

“If you have a rash, we use aquafor baby diaper cream and really up the bare butt time.”➕

“If they start to look a little red, apply sudacream in a thin layer for the next few nappies and it’s always done the trick.”➕

Compare On All Talked About Dimensions

Product Name	Price	Score	See Details	Buy Now
Balmex Complete Protection Daily Baby Diaper Rash Cream	$15	8.2	Details	Buy
Desitin Maximum Strength Baby Diaper Rash Cream	$6	7.9	Details	Buy
Medline Remedy Clinical Zinc Oxide Paste Skin Protectant	$9	7.8	Details	Buy
Burt's Bees Baby Diaper Rash Ointment	$13	7.7	Details	Buy
Boudreaux's Butt Paste Maximum Strength Diaper Rash Cream	$6	7.6	Details	Buy
A+D Original Diaper Rash Ointment 4oz	$5	7.2	Details	Buy
Desitin Daily Defense Baby Diaper Rash Cream	$4	7.1	Details	Buy
Babo Botanicals Sensitive Baby Diaper Cream	$13	6.3	Details	Buy
A+D Overnight Healing Diaper Rash Ointment	$6	6.3	Details	Buy
Mustela Baby Diaper Rash Cream 123	$12	5.6	Details	Buy
Earth Mama Organic Economy Size Diaper Balm	$21	5.2	Details	Buy
Weleda Baby Calendula Diaper Cream	$10	5.1	Details	Buy
Boudreaux's Butt Paste for Sensitive Skin Diaper Rash Cream	$6	4.6	Details	Buy
The Honest Company Hypoallergenic Diaper Rash Cream	$9	4.0	Details	Buy

Core Power Plays

The specs and strengths that make it shine.

Preference for non-petroleum based products

“I really like both the Burt's Bees diaper cream with zinc oxide for bad rashes and the Burts Bees all-purpose ointment for literally everything.”➕

Hidden Hero Hacks

Unexpected tricks and side‑door uses you’ll love.

Mixing with other products for ease of use

“we mix the desitin with aquaphor so it is easier to clean.”➕

“We mix triple paste and aquaphor and have found that to me the magic mix.”➕

Used by adults for various skin issues

“interesting!! great to hear i’ll give it a go!!”➕

Users prefer mixing with other creams

“I have like, all the creams, and use whatever speaks to my heart in the moment.”➕

Discussion about using alternative creams

“Maybe try that?”➕

Users apply diaper cream for acne treatment

“Diaper Cream is my HG for cystic acne!!!!!! I woke up in the morning amazed!”➕

“But I use Burt's Bees Diaper Cream, which is 40% zinc oxide. It works too!”➕

“I get sudocrem in the UK! It’s marketed for diaper rash, but it’s great for pimples or even chub rub.”➕

“I applied a gob of diaper rash ointment on each spot overnight. It never developed into a monster; yay!”➕

Discussion of alternative diaper creams

“Make sure you grab the extra strength as the normal one is only 15%.”➕

“It’s so good.”➕

“Hello bello diaper rash cream is also 40% zinc oxide!”➕

“Our holy grail diaper cream is welida calendula diaper cream.”➕

Preference for alternative diaper creams

“My go-to is CJ's BUTTer.”➕

“I like Burts Bees all-purpose healing ointment for protective use.”➕

Buyer’s Cheat Sheet

What to check before you click ‘Add to Cart.’

Application technique affects effectiveness

“The skin has to be completely dry before applying otherwise a rash forms.”➕

“We've always used Desitin and it's been amazing, so I don't think the product itself is terrible, but it might not work for all babies.”➕

“I'll try patting him down dry completely to make sure and see how it works from there.”➕

“In case you’re not already doing - after you use the wet wipes, use a cloth to pat dry before putting on the diaper cream.”➕

Preference for alternative products

“I absolutely love Earth Mama and plan to use it again with second baby.”➕

“CJ’s butter paste!”➕

Comparison with other diaper rash creams

“It's basically the same thing (40% zinc oxide) but with more natural ingredients.”➕

Application techniques vary among users

“Should I be using diaper cream right now? We have some, but it remains unused.”➕

“I apply it during his “last” diaper change before I put him down for the evening.”➕

“We only used it when you see a rash developing.”➕

Discussion about cost-effectiveness compared to other brands

“Seems like a potential $ savings that I can use for shoes instead 🤓”➕

Importance of air drying to prevent diaper rash

“This should really be higher, having dry skin before a new diaper is what keeps our baby rash free more than anything else.”➕

“It makes such a huge difference.”➕

“she squirms and lifts her legs up when we blast her butt with the fan lolp”➕

“Big plus of the fan is getting an extra pee at changing time.”➕

Cautionary Callouts

Know the pitfalls before they catch you off guard.

Preference for alternative products like Aquaphor

“GAME CHANGER. The next day his butt wasn't red and pimply..within the week, the lesions started to really shrink.”➕

“Aquafor is amazing, and cleared our babies nappy rash so quickly it looked like it wasn't even there after one night.”➕

“Aquafor helped instantly! Def recommend! I'm tossing everything else.”➕

Discussion about diaper brand sensitivity

“You might consider a different brand diaper if you haven’t already, my niece was like this, turned out she was mildly allergic to her diaper!”➕

“Blistered rash sounds so painful. Poor baby!”➕

Diaper brand sensitivity may affect rash occurrence

“Have you done a trial and error with diapers? She may be having a reaction to the brand.”➕