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Desitin Maximum Strength Baby Diaper Rash Cream

Curated from 138 real Reddit conversations

Refreshed on: March 18, 2025

Desitin Maximum Strength Baby Diaper Rash Cream

Brand: Desitin
Price: $6
Snoop Score:
7.9
Sentiment
6.4
Popularity
7.6
Technical
8.5

Snoop's Take

Desitin Maximum Strength Baby Diaper Rash Cream is a powerful treatment designed to alleviate and prevent diaper rash in infants. With 40% zinc oxide, this hypoallergenic paste forms a protective barrier, soothing irritated skin and providing up to 12 hours of protection from moisture. Consumer sentiment reveals strong praise for Desitin's effectiveness, with many users stating that it effectively treats diaper rashes and prevents them from occurring. "This cream is awesome 👌" and "Desitin works soooo good for us, both at treating and preventing" highlight the positive experiences shared by parents. However, some users have pointed out that it can cause irritation for sensitive skin, indicating that individual results may vary. Overall, Desitin Maximum Strength Diaper Rash Cream is highly recommended for its efficacy in treating and preventing diaper rash, particularly for those whose babies do not have super sensitive skin. It stands out in its category as a reliable choice for many parents seeking relief for their little ones.

Not for you? Check out our other rated Diaper Creams

We use that and it treats diaper rash well.

Positive Feedback

Desitin DOES NOT work for our LO who has sensitive skin.

Negative Feedback
Product
7.9
Desitin Maximum Strength Baby Diaper Rash Cream
Treating Diaper Rash Discomfort
7 / 10
Preventing Rash with Barrier Protection
6 / 10
Daily Gentle Care for Sensitive Skin
1 / 10
Overnight Protection
8 / 10
See how this compares to all Diaper Creams

What it does well!

Key strengths users can’t stop talking about.
Effectively treats diaper rash
We use that and it treats diaper rash well.
We’ve used diaper cream with every change!
Sudocrem - worked pretty well on some stubborn diaper rashes.
I typically saved this for when I had a particularly bad or stubborn rash.
Effective for treating diaper rash
This cream is awesome 👌
So far rashes have cleared in 1-2 applications
We use triple paste too and it’s been great. We’ve also used the aquaphor diaper rash cream with zin
You will need a combination of them, depending on the severity of the rash. No active rash and you
Effective for treating severe diaper rash
For really bad rash, we switch to disposables and Max strength desitin for a few days.
Effective in treating diaper rash
What diaper rash cream actually sticks to little lesions on bum?
Provides long-lasting protection
I apply it during his “last” diaper change before I put him down for the evening.
Soothing for skin irritation
The zinc oxide is an anti inflammatory and it’s just so soothing.
It's amazing.
Effective in preventing diaper rash
He’s barely had any rashes this way :)
if we don't slather down her butt before the overnight she wakes up with a rash.
Works effectively for treatment and prevention
Diaper rash cream What is your preferred cream to *treat* diaper area rashes? My LO seems prone espe
Desitin works soooo good for us, both at treating and preventing.
This stuff is LEGIT.
No issues for us.
Recommended by pediatricians
this was the only thing they would recommend.
Effective for long-lasting protection
An overnight miracle.
Effective for preventing diaper rash
haven’t had a diaper rash since she was 2 weeks old.
Works like a charm.
Only had to deal with 1 almost rash with one of them because of the preventative strategy we use with the diaper cream🙂
Creates a moisture barrier to prevent diaper rash
Is it a bad idea to use desitin extra strength every diaper change long term to prevent further rashes?
I’d say slather it on.
Using that or Vaseline or something similar is a barrier so it protects the skin from the pee/poo.
Safe for frequent application
I’ve definitely used diaper cream multiple times a day for a while after a bad diaper rash. So no harm there.
Effective for treating acne
This diaper cream had done what none of my acid-pink spot treatment-sulfur-clay mask spot treatments could do, and made all of my horrendous cystic pimples come to a head.
My guess is that this works similar to a drawing salve to bring acne to the surface, and the zinc is healing, as well.
it’s been magical ✨✨✨ But seriously, how DOES it work?

Where it needs some work!

Areas to watch—feedback on possible improvements.
Can cause diaper rashes for sensitive skin
Desitin DOES NOT work for our LO who has sensitive skin.
Little diaper rash turned into a big issue after applying it.
Sticky and hard to remove
maybe the irritation is coming from how sticky it is/hard to remove ??
anything with zinc actually made it worse but we saw overnight improvement when we only used aquaphor.
Contains fragrance which may irritate sensitive skin
Desitin Max Strength has fragrance, so maybe your baby is sensitive to that?
Can irritate sensitive skin
Something in Desitin bothered my son's skin and I found Aquaphor to be better for him.
Not preferred over other brands
I really don’t like using destine and I’m wondering what products you guys use?
Can be sticky and hard to remove
It is very sticky, but I also lathered on a lot (was desperate). My suggestion is to use a peri bottle.
Should only be used when a rash develops
You'll know when you need to use it!
Things with zinc oxide IMO should only be used when your baby actually has a rash.
Can dry out sensitive skin
The desitin ended up drying her skin so bad she started to peel down there on top of her rash.
Can cause irritation for sensitive skin
I know other babies who never used it and never had diaper rash.
my niece was like this, turned out she was mildly allergic to her diaper!
Less effective compared to other brands
I found it worked better than desitin and less messy.

Compare On All Talked About Dimensions

Product NameImagePriceScoreCompareSee DetailsBuy Now
Balmex Complete Protection Daily Baby Diaper Rash CreamBalmex Complete Protection Daily Baby Diaper Rash Cream$15
8.2
DetailsBuy
Desitin Maximum Strength Baby Diaper Rash CreamDesitin Maximum Strength Baby Diaper Rash Cream$6
7.9
DetailsBuy
Medline Remedy Clinical Zinc Oxide Paste Skin ProtectantMedline Remedy Clinical Zinc Oxide Paste Skin Protectant$9
7.8
DetailsBuy
Burt's Bees Baby Diaper Rash OintmentBurt's Bees Baby Diaper Rash Ointment$13
7.7
DetailsBuy
Boudreaux's Butt Paste Maximum Strength Diaper Rash CreamBoudreaux's Butt Paste Maximum Strength Diaper Rash Cream$6
7.6
DetailsBuy
A+D Original Diaper Rash Ointment 4ozA+D Original Diaper Rash Ointment 4oz$5
7.2
DetailsBuy
Desitin Daily Defense Baby Diaper Rash CreamDesitin Daily Defense Baby Diaper Rash Cream$4
7.1
DetailsBuy
Babo Botanicals Sensitive Baby Diaper CreamBabo Botanicals Sensitive Baby Diaper Cream$13
6.3
DetailsBuy
A+D Overnight Healing Diaper Rash OintmentA+D Overnight Healing Diaper Rash Ointment$6
6.3
DetailsBuy
Mustela Baby Diaper Rash Cream 123Mustela Baby Diaper Rash Cream 123$12
5.6
DetailsBuy
Earth Mama Organic Economy Size Diaper BalmEarth Mama Organic Economy Size Diaper Balm$21
5.2
DetailsBuy
Weleda Baby Calendula Diaper CreamWeleda Baby Calendula Diaper Cream$10
5.1
DetailsBuy
Boudreaux's Butt Paste for Sensitive Skin Diaper Rash CreamBoudreaux's Butt Paste for Sensitive Skin Diaper Rash Cream$6
4.6
DetailsBuy
The Honest Company Hypoallergenic Diaper Rash CreamThe Honest Company Hypoallergenic Diaper Rash Cream$9
4.0
DetailsBuy

Core Power Plays

The specs and strengths that make it shine.
Thanks for helpful responses
these responses were really helpful.
Discussion on various diaper creams preferences
Best diaper rash cream I’m having a baby girl in Jan.
Our go to is Boudreaux's Butt Paste but in the GREEN tube (safe for cloth diapers) but the zinc will cause staining.
we have never even gotten close to finishing a tube of diaper cream.
I preferred to use the faster acting cream over keeping the diapers pristine in that case.

Hidden Hero Hacks

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Discussion on using diaper cream for non-diaper rash issues
But I use Burt's Bees Diaper Cream, which is 40% zinc oxide. It works too!
I just pop a bit on before bed, and I wake up with it reduced and less red.

Buyer’s Cheat Sheet

What to check before you click ‘Add to Cart.’
Discussion on proper application technique
The skin has to be completely dry before applying otherwise a rash forms.
We've always used Desitin and it's been amazing, so I don't think the product itself is terrible.
I'll try patting him down dry completely to make sure and see how it works from there.
Aquaphor after every poopy diaper, but don't reapply for just pee diapers, have never had a diaper rash.
Discussion on diaper rash cream recommendations
I felt terrible and will never use the tubby Todd again at all.
I swear by Boudreaux’s butt paste.
It’s definitely thicker than other diaper rash creams that I’ve used before.
Agreed this is the best.
Advice on application techniques
In case you’re not already doing - after you use the wet wipes, use a cloth to pat dry before putting on the diaper cream.
Discussion on alternative diaper rash creams
I never see Bordeauxs green butt cream mentioned here, which is not petroleum based and has zinc.
We use the green Budreaux’s, too! Works just fine.
Cloth diaper mama here….we use green Boudreaux or just plain lanolin! Works great.
We like Weleda.
Advice on proper application techniques
the skin and rashy area needs to be DRY DRY DRY before you apply.
We would put destin/butt paste then a layer of aquafor or Vaseline to keep it in place.
Desitin and buttpaste are more zinc oxide based, so a little more heavy duty use for rash than the others.
Doctor recommended for various skin issues
i trust my doctor and i know it’s for baby’s so it must be sensitive enough for adults.
Comparison to other diaper rash creams
It's basically the same thing (40% zinc oxide) but with more natural ingredients.
Sudocrem for the win!
Advice on combining different creams based on rash severity
Discovering the wide range of uses for nipple cream has been life changing for me.
Discussion on application techniques
Just apply a thin layer and make sure the area is bone dry beforehand!
Yep! The kind with zinc oxide in it. It works so fast.
Discussion on diaper application methods
So my daughter is 15 weeks…and I’ve been putting a swipe of diaper cream at every change.
Nope. I only put it on when I see red skin.
Other than that I let her lay naked on the changing table for a couple minutes during diaper changes to dry.
Advice on application frequency
I use diaper cream whenever her diaper area is looking red, but not every diaper change.
Discussion on trial and error with diaper brands
Personally I wouldn’t put cream on every time if her rash is cleared up.
Alternatives to Desitin for diaper rash prevention
Maybe try that?

Cautionary Callouts

Know the pitfalls before they catch you off guard.
Family history of sensitivity to the product
A particularly bad or persistent diaper rash is absolutely a reason to make an appointment with the pediatrician!
Hesitance to use on sensitive skin
i’ve been hesitant to put anything on the skin that is freaked out lol but i just bought a bottle last night so i’ll definitely start using it.

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